Neurotoxin‑induced rodent models of Parkinson’s disease: benefits and drawbacks

• Main Authors: El-Gamal, Mohamed, Salama, Mohamed, Collins-Praino, Lyndsey E., Baetu, Irina, Fathalla, Ahmed M., Soliman, Amira M., Mohamed, Wael Mohamed Yousef, Moustafa, Ahmed A.
• Format: Article
• Language: English; English; English
• Published: Springer Nature 2021
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/89053/15/89053_new_1.pdf; http://irep.iium.edu.my/89053/8/89053_Neurotoxin%E2%80%91induced%20rodent%20models%20of%20Parkinson%E2%80%99s%20disease%20benefits%20and%20drawbacks.pdf; http://irep.iium.edu.my/89053/26/89053_Neurotoxin%E2%80%91induced%20rodent%20models_Scopus.pdf; http://irep.iium.edu.my/89053/; https://link.springer.com/article/10.1007/s12640-021-00356-8

Parkinson’s disease (PD), the second most common neurodegenerative disorder, is characterized by cardinal motor impair-ments, including akinesia and tremor, as well as by a host of non-motor symptoms, including both autonomic and cognitive dysfunction. PD is associated with a death of nigral dopamin...