Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres )
The recent diagnostic assessment of cerebrovascular disease makes use of computational fluid dynamics (CFD) to quantify blood flow and determine the hemodynamics factors contributing to the disease from patient-specific models. However, compliant, and anatomical patient-specific geometries are gener...
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my.iium.irep.883012021-02-09T09:47:50Z http://irep.iium.edu.my/88301/ Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) Lim, Sheh Hong Mohd Adib, Mohd Azrul Hisham Abdullah, Mohd Shafie Mohd Taib, Nur Hartini Hassan, Radhiana Abd. Aziz, Azian RC Internal medicine The recent diagnostic assessment of cerebrovascular disease makes use of computational fluid dynamics (CFD) to quantify blood flow and determine the hemodynamics factors contributing to the disease from patient-specific models. However, compliant, and anatomical patient-specific geometries are generally reconstructed from the medical images with different threshold values subjectively. Therefore, this paper tends to present the effect of extracted geometry with different threshold coefficient, Ctℎres by using a patient-specific cerebral aneurysm model. A set of medical images, digital subtraction angiography (DSA) images from the real patient diagnosed with internal carotid artery (ICA) aneurysm was obtained. The threshold value used to extract the patient-specific cerebral aneurysm geometry was calculated by using a simple threshold determination method. Several threshold coefficients, Ctℎres such as 0.2, 0.3, 0.4, 0.5 and 0.6 were employed in the image segmentation creating three-dimensional (3D) realistic arterial geometries that were then used for CFD simulation. As a result, we obtained that the volume of each patient-specific cerebral aneurysm geometry decreases as the threshold coefficient, Ctℎres increases. There is dislocation of artery attached to the ICA aneurysm geometry occurred at a high threshold coefficient, Ctℎres . Besides, the physical changes also bring remarkable physiological effect on the wall shear stress (WSS) distribution and velocity flow field at the patient-specific cerebral aneurysm geometry reconstructed with different threshold coefficient, Ctℎres Penerbit Akademia Baru 2020-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/88301/1/88301_Study%20of%20extracted%20geometry%20effect.pdf application/pdf en http://irep.iium.edu.my/88301/2/88301_Study%20of%20extracted%20geometry%20effect_SCOPUS.pdf Lim, Sheh Hong and Mohd Adib, Mohd Azrul Hisham and Abdullah, Mohd Shafie and Mohd Taib, Nur Hartini and Hassan, Radhiana and Abd. Aziz, Azian (2020) Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ). CFD Letters, 12 (10). pp. 1-14. ISSN 21801363 http://akademiabaru.com/submit/index.php/cfdl/article/view/844/733 10.37934/cfdl.12.10.114 |
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RC Internal medicine Lim, Sheh Hong Mohd Adib, Mohd Azrul Hisham Abdullah, Mohd Shafie Mohd Taib, Nur Hartini Hassan, Radhiana Abd. Aziz, Azian Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
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The recent diagnostic assessment of cerebrovascular disease makes use of computational fluid dynamics (CFD) to quantify blood flow and determine the hemodynamics factors contributing to the disease from patient-specific models. However, compliant, and anatomical patient-specific geometries are generally reconstructed from the medical images with different threshold values subjectively. Therefore, this paper tends to present the effect of extracted geometry with different threshold coefficient, Ctℎres by using a patient-specific cerebral aneurysm model. A set of medical images, digital subtraction angiography (DSA) images from the real patient diagnosed with internal carotid artery (ICA) aneurysm was obtained. The threshold value used to extract the patient-specific cerebral aneurysm geometry was calculated by using a simple threshold determination method. Several threshold coefficients, Ctℎres such as 0.2, 0.3, 0.4, 0.5 and 0.6 were employed in the image segmentation creating three-dimensional (3D) realistic arterial geometries that were then used for CFD simulation. As a result, we obtained that the volume of each patient-specific cerebral aneurysm geometry decreases as the threshold coefficient, Ctℎres increases. There is dislocation of artery attached to the ICA aneurysm geometry occurred at a high threshold coefficient, Ctℎres . Besides, the physical changes also bring remarkable physiological effect on the wall shear stress (WSS) distribution and velocity flow field at the patient-specific cerebral aneurysm geometry reconstructed with different threshold coefficient, Ctℎres |
format |
Article |
author |
Lim, Sheh Hong Mohd Adib, Mohd Azrul Hisham Abdullah, Mohd Shafie Mohd Taib, Nur Hartini Hassan, Radhiana Abd. Aziz, Azian |
author_facet |
Lim, Sheh Hong Mohd Adib, Mohd Azrul Hisham Abdullah, Mohd Shafie Mohd Taib, Nur Hartini Hassan, Radhiana Abd. Aziz, Azian |
author_sort |
Lim, Sheh Hong |
title |
Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
title_short |
Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
title_full |
Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
title_fullStr |
Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
title_full_unstemmed |
Study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (Ctℎres ) |
title_sort |
study of extracted geometry effect on patient-specific cerebral aneurysm model with different threshold coefficient (ctℎres ) |
publisher |
Penerbit Akademia Baru |
publishDate |
2020 |
url |
http://irep.iium.edu.my/88301/1/88301_Study%20of%20extracted%20geometry%20effect.pdf http://irep.iium.edu.my/88301/2/88301_Study%20of%20extracted%20geometry%20effect_SCOPUS.pdf http://irep.iium.edu.my/88301/ http://akademiabaru.com/submit/index.php/cfdl/article/view/844/733 |
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1691732936668217344 |
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13.188475 |