The assessment of three dimensional modelling design for single strand DNA aptamers for computational chemistry application

• Main Authors: Sabri, Mohamad Zulkeflee, Abdul Hamid, Azzmer Azzar, Sayed Hitam, Sharifah Mariam, Abdul Rahim, Mohd. Zulkhairi
• Format: Article
• Language: English; English; English
• Published: Elsevier B.V. 2020
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/88194/1/88194_The%20assessment%20of%20three%20dimensional%20modelling.pdf; http://irep.iium.edu.my/88194/2/88194_The%20assessment%20of%20three%20dimensional%20modelling_SCOPUS.pdf; http://irep.iium.edu.my/88194/3/88194_The%20assessment%20of%20three%20dimensional%20modelling_WoS.pdf; http://irep.iium.edu.my/88194/; https://www.sciencedirect.com/science/article/abs/pii/S0301462220302003; https://doi.org/10.1016/j.bpc.2020.106492

Aptamers are oligonucleotides and peptides around 15–100 bases in length and are suitable as detection probes or as therapeutics molecules. There are growing interests in the aptamer screening approach through computational simulation methods. DNA and RNA modelling lacks of validation on their predi...