Antidiabetic effects of P. macrocarpa ethanolic fruit extract in streptozotocin-induced diabetic rats

• Main Authors: Azad, Abul Kalam, Wan Sulaiman, Wan Mohd Azizi
• Format: Article
• Language: English; English
• Published: Springer 2020
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/87980/1/87980_Antidiabetic%20effects%20of%20P.%20macrocarpa%20ethanolic%20fruit_article.pdf; http://irep.iium.edu.my/87980/2/87980_Antidiabetic%20effects%20of%20P.%20macrocarpa%20ethanolic%20fruit_wos.pdf; http://irep.iium.edu.my/87980/; https://link.springer.com/article/10.1186/s43094-020-00073-7

Background: The fruits of P. macrocarpa have long been used as a traditional Malay medicinal herb for hundreds of years. Intraperitoneal (i.p.) injection of streptozotocin (STZ) (65 mg/kg) was used to induce diabetes in rats confirmed by an oral glucose tolerance test (OGTT). The ethanol extract o...