Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria
Objectives There is a paucity of data describing the prevalence of and factors associated with the use of potentially inappropriate medications (PIMs) among older adults in Northern Nigeria. This study evaluates the prevalence and predictors of PIMs used among older adults attending outpatient clini...
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my.iium.irep.875832021-01-12T01:15:22Z http://irep.iium.edu.my/87583/ Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria Abubakar, Usman Tangiisuran, Balamurugan Kolo, Mohammad Yamma, Abdulkadir Ibrahim Hammad, Mohamed Anwar Sulaiman, Syed Azhar RS Pharmacy and materia medica Objectives There is a paucity of data describing the prevalence of and factors associated with the use of potentially inappropriate medications (PIMs) among older adults in Northern Nigeria. This study evaluates the prevalence and predictors of PIMs used among older adults attending outpatient clinics. Methods This cross-sectional study involved patients aged ≥ 65 years attending outpatient clinics in two public hospitals and was conducted from June to September 2016. PIMs were detected using the American Geriatrics Society (AGS) 2015 updated Beers criteria and the Screening Tool of Older People’s potentially inappropriate Prescriptions (STOPP) [version 2] criteria. Results A total of 244 older adults (mean age 71.1 ± 6.1 years) were included. The prevalence of PIM measured using Beers (67.2%) and STOPP criteria (40.2%) varied signifcantly (p = 0.047). Both Beers and STOPP criteria identifed at least one PIM in 73 patients (29.9%). Nonsteroidal anti-infammatory drugs (NSAIDs) and α-methyldopa were the most common PIMs identifed using the Beers criteria. Concurrent use of an angiotensin-converting enzyme inhibitor and amiloride was observed in 32.4% of older adults. “Glibenclamide and glimepiride” and “NSAIDs with concurrent antiplatelet without proton pump inhibitor” were the most common PIMs detected by the STOPP criteria. The number of medications being taken and the hospital attended were signifcant predictors of PIM. Conclusion The prevalence of PIMs among ambulatory older adults was relatively high. A higher number of medications and the hospital attended were associated with a greater risk of PIMs. The 2015 Beers criteria detected signifcantly higher PIMs than the STOPP criteria (version 2). These observations highlight the need for interventions to improve the use of medications in older adults. Springer Nature 2020-12-21 Article PeerReviewed application/pdf en http://irep.iium.edu.my/87583/13/87583%20Prevalence%20and%20predictors%20of%20potentially%20in-press.pdf application/pdf en http://irep.iium.edu.my/87583/14/87583%20Prevalence%20and%20predictors%20of%20potentially%20SCOPUS%20in-press.pdf Abubakar, Usman and Tangiisuran, Balamurugan and Kolo, Mohammad and Yamma, Abdulkadir Ibrahim and Hammad, Mohamed Anwar and Sulaiman, Syed Azhar (2020) Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria. Drugs & Therapy Perspectives. ISSN 1172-0360 E-ISSN 1179-1977 (In Press) https://link.springer.com/article/10.1007/s40267-020-00800-3 https://doi.org/10.1007/s40267-020-00800-3 |
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RS Pharmacy and materia medica Abubakar, Usman Tangiisuran, Balamurugan Kolo, Mohammad Yamma, Abdulkadir Ibrahim Hammad, Mohamed Anwar Sulaiman, Syed Azhar Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
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Objectives There is a paucity of data describing the prevalence of and factors associated with the use of potentially inappropriate medications (PIMs) among older adults in Northern Nigeria. This study evaluates the prevalence and predictors of PIMs used among older adults attending outpatient clinics.
Methods This cross-sectional study involved patients aged ≥ 65 years attending outpatient clinics in two public hospitals and was conducted from June to September 2016. PIMs were detected using the American Geriatrics Society (AGS) 2015 updated Beers criteria and the Screening Tool of Older People’s potentially inappropriate Prescriptions (STOPP) [version 2] criteria.
Results A total of 244 older adults (mean age 71.1 ± 6.1 years) were included. The prevalence of PIM measured using Beers
(67.2%) and STOPP criteria (40.2%) varied signifcantly (p = 0.047). Both Beers and STOPP criteria identifed at least one
PIM in 73 patients (29.9%). Nonsteroidal anti-infammatory drugs (NSAIDs) and α-methyldopa were the most common
PIMs identifed using the Beers criteria. Concurrent use of an angiotensin-converting enzyme inhibitor and amiloride was
observed in 32.4% of older adults. “Glibenclamide and glimepiride” and “NSAIDs with concurrent antiplatelet without proton pump inhibitor” were the most common PIMs detected by the STOPP criteria. The number of medications being taken and the hospital attended were signifcant predictors of PIM.
Conclusion The prevalence of PIMs among ambulatory older adults was relatively high. A higher number of medications
and the hospital attended were associated with a greater risk of PIMs. The 2015 Beers criteria detected signifcantly higher
PIMs than the STOPP criteria (version 2). These observations highlight the need for interventions to improve the use of
medications in older adults. |
format |
Article |
author |
Abubakar, Usman Tangiisuran, Balamurugan Kolo, Mohammad Yamma, Abdulkadir Ibrahim Hammad, Mohamed Anwar Sulaiman, Syed Azhar |
author_facet |
Abubakar, Usman Tangiisuran, Balamurugan Kolo, Mohammad Yamma, Abdulkadir Ibrahim Hammad, Mohamed Anwar Sulaiman, Syed Azhar |
author_sort |
Abubakar, Usman |
title |
Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
title_short |
Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
title_full |
Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
title_fullStr |
Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
title_full_unstemmed |
Prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in Northern Nigeria |
title_sort |
prevalence and predictors of potentially inappropriate medication use among ambulatory older adults in northern nigeria |
publisher |
Springer Nature |
publishDate |
2020 |
url |
http://irep.iium.edu.my/87583/13/87583%20Prevalence%20and%20predictors%20of%20potentially%20in-press.pdf http://irep.iium.edu.my/87583/14/87583%20Prevalence%20and%20predictors%20of%20potentially%20SCOPUS%20in-press.pdf http://irep.iium.edu.my/87583/ https://link.springer.com/article/10.1007/s40267-020-00800-3 https://doi.org/10.1007/s40267-020-00800-3 |
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1688646780847128576 |
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13.160551 |