Metabolomics as new tool in pharmacognosy

• Main Author: Khatib, Alfi
• Format: Conference or Workshop Item
• Language: English; English; English; English
• Published: 2019
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/87534/1/certificate%20metabolomics.jpg; http://irep.iium.edu.my/87534/2/Invitation%20letter.pdf; http://irep.iium.edu.my/87534/3/IIUM.pdf; http://irep.iium.edu.my/87534/4/metabolomics%20as%20a%20new%20tools%20in%20pharmacogosy.pdf; http://irep.iium.edu.my/87534/

A latest definition of pharmacognosy includes data pooling obtained from system biology and chemo-informatics, This approach requires a holistic and comprehensive analysis of metabolites in samples which is called metabolomics. Some application of this approach in pharmacognosy lies in 3 areas as follows: - Analysis of known bio-active compounds and screening of metabolites in the extracts prior to isolation of unknown bio-active compounds. - Analytical tool in quality control and process optimization of herbal products based on the fingerprint of their metabolites. - Comprehensive bio-activity and toxicity evaluation of the herbal products. In this lecture, several medicinal Malaysia herbs are used as an example such as Clinacanthus nutans, Momordica charantia, and Psychotria malayana.