Multi-drug resistant neisseria gonorrhea among hotel-based sex workers in Rajshahi, Bangladesh
Abstract: Information on antimicrobial sensitivity pattern of Neisseria gonorrhea among commercial sex workers in worldwide many cities have already been reported but are yet to be investigated in Rajshahi city, Bangladesh. This study aimed to determine the antimicrobial resistance profile in N. go...
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| Format: | Article |
| Language: | English |
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IDOSI Publications
2013
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| Online Access: | http://irep.iium.edu.my/87197/1/MDR-gonococci.pdf http://irep.iium.edu.my/87197/ |
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| Summary: | Abstract: Information on antimicrobial sensitivity pattern of Neisseria gonorrhea among commercial sex workers in worldwide many cities have already been reported but are yet to be investigated in Rajshahi city,
Bangladesh. This study aimed to determine the antimicrobial resistance profile in N. gonorrhea among hotel-based sex workers in this city. N. gonorrhea strain was isolated from endocervical swab specimen from
sex workers and identified by biochemical analysis. In vitro susceptibility test of gonorrhea isolates was performed by disk diffusion method with traditional and widely used antimicrobials, e.g. penicillin, tetracycline,
ciprofloxacin, erythromycin, ceftriaxone and cefixime. Sex workers’ mean age ranged 20-30 years having either hidden or obvious gonococcal infection. All isolated N. gonorrhea strains were highly or intermediately
resistant against tetracycline, penicillin, ciprofloxacin, ceftriaxone. High-level resistance was found in three isolates against tetracycline, erythromycin and ciprofloxacin. Eythromycin was resistant against three
isolates but was highly active against one isolate. Only cefixime was potentially active against all isolates indicating that cefixime is currently the choice of drug for gonorrhea treatment. However, tested antibiotics
exhibited a case-specific effectiveness on gonorrhea isolates. Obtained drug resistance pattern varied on the case of individual, some other factors associated with lifestyle of individual and geographic location. Multi-drug resistant N. gonorrhea was in alerting level that bears a risk of transmission of STD to general public. The need of surveillance and counseling to sex workers, prevention and control of infection should be undertaken seriously otherwise it would cause a devastating epidemic in near future. |
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