Receptor-based combinatorial nanomedicines: a new hope for cancer management
Nanotechnology-based drug-delivery systems, as an anticancer therapy tool, have shown significant potentials for the diagnosis and treatment of cancer. Recent studies have demonstrated that cancer therapy could be efficiently achieved by combinatorial therapies, approaches using multiple drug regim...
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| Main Authors: | , , , , , |
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| Format: | Book Chapter |
| Language: | English |
| Published: |
IGI Global
2020
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/85894/1/85894_Receptor-based%20combinatorial%20nanomedicines.pdf http://irep.iium.edu.my/85894/ https://www.igi-global.com/chapter/receptor-based-combinatorial-nanomedicines/267048 |
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| Summary: | Nanotechnology-based drug-delivery systems, as an anticancer therapy tool, have shown significant potentials for the diagnosis and treatment of cancer. Recent studies have demonstrated that cancer therapy
could be efficiently achieved by combinatorial therapies, approaches using multiple drug regimens for
targeting cancers. However, their usages have been limited due to shorter half-lives of chemotherapeutic
agents, insignificant targetability to tumor sites and suboptimal levels of co-administered conventional
drug moieties. Thus, nanotechnology-based drug-delivery systems with effective targetability have
played a crucial role to overcome the limitations and challenges associated with conventional therapies and also have provided greater therapeutic efficacy. Herein, the authors have focused on various
drug-incorporated combinatorial nanocarrier systems, the significance of various receptors-associated
strategies, and various targeted delivery approaches for chemotherapeutic agents. |
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