The role of circulating lipid chaperone proteins in insulin signalling and inflammation

• Main Authors: Mohd Radzuan, Hazulin, Bennett, Andrew J., Cole, Mark A.
• Format: Conference or Workshop Item
• Language: English
• Published: 2017
• Subjects: Q Science (General); R Medicine (General); RB Pathology; RC Internal medicine; RC627 Specialties of Internal Medicine-Metabolic Diseases; RM Therapeutics. Pharmacology; RM283 Endocrinotheraphy; RM300 Drugs and their action; RZ Other systems of medicine
• Online Access: http://irep.iium.edu.my/83667/1/MySECON2017-%20BOOK%20FINAL.pdf; http://irep.iium.edu.my/83667/

A growing body of evidence indicates that adipose tissue actively secretes lipid chaperone proteins into circulatory system, such as fatty acid binding protein4 (FABP4) and lipocalin2 (LCN2). FABP4 have been implicated in the pathogenesis of obesity-induced insulin resistance, whereas role of LCN2 i...