Association between metabolic syndrome components and blood pressure in young adults: evidence from Kuantan, Malaysia

• Main Authors: Wan Omar, Wan Fatein Nabeila, A.Talib, Norlelawati, Abdullah, Aszrin, Ab Rahman, Jamalludin, Mohd Shah, Azarisman Shah
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2019
• Subjects: QP Physiology; RC627 Specialties of Internal Medicine-Metabolic Diseases; RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
• Online Access: http://irep.iium.edu.my/83534/4/POSTER%20metS%20in%20PDF.pdf; http://irep.iium.edu.my/83534/25/hypertension%20seoul%202019.pdf; http://irep.iium.edu.my/83534/

Introduction: Metabolic syndrome is becoming more common among young adults regardless of blood pressure. Nevertheless, diagnosis is often delayed. The association between metabolic syndrome and blood pressure in young adults is not widely described. This study aimed to assess the association of metabolic syndrome components in young adults of varying blood pressure. Methods: This study employed data from a previous healthy, non-diabetic young adult cohort conducted in Kuantan in 2016-2017. Respondents aged 18 to 45 years were grouped to normotension, prehypertension and newly-diagnosed hypertension using The Seventh Report of the Joint National Committee (JNC7) definition with n=80 respectively. Fasting blood was analysed for biochemical profiles and anthropometrics were measured. Metabolic syndrome was assessed using 2009 Joint Interim Statement (JIS) criteria. Results: The overall proportion of young adults with metabolic syndrome was 26.3%. It affected almost half of newly-diagnosed hypertensive and more than quarter of prehypertensive subjects. Fifty eight percent of the cohort had at least two components, and those with higher blood pressure have more components. Central obesity is the most prevalent component in all groups, followed by hypertriglyceridemia, and low HDL cholesterol in hypertension, and prehypertension respectively. Conclusion: Metabolic syndrome and its components were common in newly-diagnosed prehypertensive and hypertensive young adults. This data could reflect the entire young adult population in Malaysia. This warrants intensive screening for early detection of co-existence of other components and stronger reinforcement of health awareness in these population. Addressing the abnormal metabolic parameters by emphasizing healthy lifestyle modification could reduce further cardiovascular risk.