Phytochemicals with antifungal properties: Cure from nature
Aims: The exploration of natural products with innovative uses is dynamic and expanding rapidly. Medicinal plants have fascinated many researchers that subsequently lead to research publications highlighting plant extracts with wide range of secondary metabolites such as flavonoids, alkaloids, gly...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English English English |
| Published: |
2020
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/81995/1/elgharbawy%20et%20al.%202020_mjm.pdf http://irep.iium.edu.my/81995/3/Malaysian%20Journal%20of%20Microbiology_MyJurnal%20-%20Malaysia%20Citation%20Centre.pdf http://irep.iium.edu.my/81995/5/Malaysian%20Journal%20of%20Microbiology_Web%20of%20Science%20Master%20Journal%20List%20-%20Journal%20Profile.pdf http://irep.iium.edu.my/81995/32/81995_Phytochemicals%20with%20antifungal%20properties_SCOPUS.pdf http://irep.iium.edu.my/81995/ |
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| Summary: | Aims: The exploration of natural products with innovative uses is dynamic and expanding rapidly. Medicinal plants have
fascinated many researchers that subsequently lead to research publications highlighting plant extracts with wide range
of secondary metabolites such as flavonoids, alkaloids, glycosides, quinones, terpenoids, tannins and saponins that
exhibit antimicrobial activities and disease control. The concentration of these bioactive compounds in each plant
species varies based on the pathosystem and environmental conditions. This study aims to uncover the various types of
phytochemicals with antifungal properties.
Methodology and results: Seven categories of plant-based antifungal compounds were reviewed, which are
terpenoids, saponins, phenolic compounds, coumarins, alkaloids, essential oils and peptides, with examples and
structures of some available compounds. The mechanism of action of each category of phytochemical was discussed.
Also, the impact of some compounds was explained and elaborated.
Conclusion, significance and impact of study: It is of a great importance to explore natural plant fighters against
fungal infection. Those active plant components do not only have antifungal properties, but they also help in the healing
process and some even exhibit anticancer activities. The development and knowledge of antifungal activities from plant
extracts have the potential for applications in antifungal therapy. Since the exact description of how antifungal
compounds function in the human body is still unclear more studies are required to unveil phytochemicals’ properties
and to elucidate their effects on living cells. |
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