Angiotensin II type 1 receptor (AGTR1) methylation is inversely associated with HbA1c level in non-diabetic young adults

• Main Authors: Wan Omar, Wan Fatein Nabeila, A.Talib, Norlelawati, Mohd. Shah, Aida Nur Sharini, Mohd Shah, Azarisman Shah, Abdullah, Aszrin
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2019
• Subjects: QH426 Genetics; QP Physiology
• Online Access: http://irep.iium.edu.my/81675/7/poster%20COSS.pdf; http://irep.iium.edu.my/81675/12/Biomedical%20Cambridge-Oxford-Sunway%20Symposium%20program%20book.pdf; http://irep.iium.edu.my/81675/

Introduction: The increasing incidence of early onset type 2 diabetes worldwide is worrying. Epigenetics may play a role in the pathophysiology of insulin resistance and glucose intolerance. It is hypothesized that overexpression of angiotensin II type 1 receptor (AGTR1) in pancreas impairs insulin...