Matrix production in chondrocytes transfected with sex determining region Y-Box 9 and telomerase reverse transcriptase genes: an in vitro evaluation from monolayer culture to three-dimensional culture

• Main Authors: Md Nazir, Noorhidayah, Zulkifly, Ahmad Hafiz, Khalid, Kamarul Ariffin, Zainol, Ismail, Zamli, Zaitunnatakhin, Sha'ban, Munirah
• Format: Article
• Language: English; English; English
• Published: Korean Tissue Engineering and Regenerative Medicine Society 2019
• Subjects: RA Public aspects of medicine
• Online Access: http://irep.iium.edu.my/79713/1/79713_Matrix%20Production%20in%20Chondrocytes_MYRA.pdf; http://irep.iium.edu.my/79713/2/79713_Matrix%20Production%20in%20Chondrocytes_SCOPUS.pdf; http://irep.iium.edu.my/79713/3/79713_Matrix%20Production%20in%20Chondrocytes_WOS.pdf; http://irep.iium.edu.my/79713/; https://link.springer.com/article/10.1007/s13770-019-00191-1

Background:: This study aimed to observe the cartilaginous matrix production in SRY (sex determining region Y)-box 9 (SOX9)- and/or telomerase reverse transcriptase (TERT)-transfected chondrocytes from monolayer to three-dimensional (3D) culture. Methods:: The genes were transferred into chondrocyte...