Electrospun pva-graphene oxide-pedot: PSS nanofibers for wound healing

• Main Authors: Barthasarathy, Piravin Raj, Ahmad Shahizam, Zayd, Wan Salim, Wan Wardatul Amani
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2019
• Subjects: QD Chemistry; RL Dermatology; TP Chemical technology
• Online Access: http://irep.iium.edu.my/77401/1/ACS%20Poster_Piravin%20et%20al%202019.pdf; http://irep.iium.edu.my/77401/2/ACS%20on%20Campus%202019.pdf; http://irep.iium.edu.my/77401/

Electrical fiber spinning, or electrospinning is a common technique adopted to produce nanofibers (diameter ˂ 500 nm) [1]. Nanofibers-based scaffolds are highly valued for their mechanical and biological properties [1]. Nanofibers composed of different nanofillers posed enormous challenges in emulating the architecture of the extracellular matrix [1]. We have capitalized on the unique property of graphene oxide (GO) and poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) as nanofillers. GO has been used as a carrier for drug [2] & gene delivery [3] and wound healing applications [4]. SH-SY5Y neuroblastoma-derived cells and primary mouse embryonic neural cells were able to survive upon attachment to PEDOT:PSS [5]. PEDOT:PSS polymers can also act as a drug delivery platform [6].