Comparison of the in vitro and in vivo toxic effects of thymoquinone using oral cancer HSC-3 and HSC-4 cell lines, oral fibroblasts, HACAT cell line, and Zebrafish embryos

• Main Authors: How, Fiona Ni Foong, Solachuddin Jauhari, Arief Ichwan, Kasmuri, Abdul Razak
• Format: Conference or Workshop Item
• Language: English; English
• Published: Elsevier 2019
• Subjects: QD Chemistry; RK Dentistry
• Online Access: http://irep.iium.edu.my/77267/1/Materials%20Today%20Proceedings%2016%20%282019%29%202108%E2%80%932114.pdf; http://irep.iium.edu.my/77267/7/77267_Comparison%20of%20the%20in%20vitro%20and%20in%20vivo%20toxic%20effects_scopus.pdf; http://irep.iium.edu.my/77267/; https://www.journals.elsevier.com/materials-today-proceedings

The discovery and development of anticancer agents were made through long processes from screening new compounds in various cell lines, animal experimental studies, until clinical trials Majority of cancer chemotherapeutic agents have been initially screened in an in vitro cell-based system and the...