Periodic assessment of antenatal and post natal serum endothelin-1 (ET-1) and nitric oxide (NO) levels in hypertensive disorders of pregnancy (HDP)

• Main Authors: Ismawi, Hidayatul Radziah, Abdul Razak, Tariq, Jamani, Nurjasmine Aida, Mohd Zainudin, Maizura
• Format: Article
• Language: English; English; English
• Published: Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2019
• Subjects: R Medicine (General); RC Internal medicine; RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
• Online Access: http://irep.iium.edu.my/74406/1/74406_Periodic%20assessment%20of%20antenatal%20and%20post%20natal%20serum%20Endothelin-1%20%28ET-1%29%20and%20nitric%20oxide%20%28NO%29%20levels%20in%20Hypertensive%20Disorders%20of%20Pregnancy%20%28HDP%29.pdf; http://irep.iium.edu.my/74406/2/74406_Periodic%20assessment%20of%20antenatal%20and%20post%20natal%20serum%20Endothelin-1%20%28ET-1%29%20and%20nitric%20oxide%20%28NO%29%20levels%20in%20Hypertensive%20Disorders%20of%20Pregnancy%20%28HDP%29_SCOPUS.pdf; http://irep.iium.edu.my/74406/9/74406_Periodic%20assessment%20of%20antenatal%20and%20post%20natal_wos.pdf; http://irep.iium.edu.my/74406/; http://iiumedic.net/imjm/v1/download/volume_18_no_2/Pages-from-IMJMVol18No2-16.pdf

Introduction: Hypertensive Disorders of Pregnancy (HDP) is an independent risk factor of cardiovascular (CVS) disease with endothelial dysfunction postulated to be the pathophysiology. Endothelin-1 (ET-1), a potent vasoconstrictor, has been identified as a pivotal mediator in HDP. Disturbances in ni...