Oxoaporphine alkaloids from the barks of Platymitra siamensis Craib (Annonaceae) and their cytotoxicity against MCF-7 cancer cell line

• Main Authors: Shieh Ting, Kan, Ahmad, Mohamad Syahrizal, Syed Abdul Azziz, Saripah Salbiah, Awang, Khalijah, Mhd Bakri, Yuhanis, Nafiah, Mohd Azlan, Abbas, Phirdaous, Hashim, Yumi Zuhanis Has-Yun
• Format: Article
• Language: English; English
• Published: Marmara University Press 2019
• Subjects: QR180 Immunology; RC Internal medicine; RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/71573/1/71573_Oxoaporphine%20alkaloids%20from%20the%20barks%20_article.pdf; http://irep.iium.edu.my/71573/2/71573_Oxoaporphine%20alkaloids%20from%20the%20barks%20_wos.pdf; http://irep.iium.edu.my/71573/; http://jrespharm.com/uploads/pdf/pdf_MPJ_649.pdf

Study on the chemical constituents of the dichloromethane (DCM) crude extract of Platymitra siamensis Craib has led to the isolation of four oxoaporphine alkaloids. The compounds were identified as liriodenine (1), Omethylmoschatoline (2), lysicamine (3) and cepharadione-A (4) which were isolated f...