A systematic review and meta-analysis of the impact of collaborative practice between community pharmacist and general practitioner on asthma management

• Main Authors: Mubarak, Naeem, Md Hatah, Ernieda, Mehmood Khan, Tahir, Zin, Che Suraya
• Format: Article
• Language: English; English; English; English; English
• Published: Dove Press 2019
• Subjects: RM147 Administration of Drugs and Other Therapeutic Agents
• Online Access: http://irep.iium.edu.my/71513/1/190408_Revised%20Manuscript.pdf; http://irep.iium.edu.my/71513/2/190408_Acceptance_J%20Asthma%20and%20Allergy_.JPG; http://irep.iium.edu.my/71513/12/71513_A%20systematic%20review%20and%20meta-analysis%20of%20the%20impact%20of%20collaborative%20practice%20between%20community%20pharmacist%20and%20general%20practitioner%20on%20asthma%20management_WOS.pdf; http://irep.iium.edu.my/71513/18/71513_A%20systematic%20review%20and%20meta-analysis%20of%20the%20impact%20of%20collaborative%20practice_scopus.pdf; http://irep.iium.edu.my/71513/24/71513_A%20systematic%20review%20and%20meta-analysis_scopus.pdf; http://irep.iium.edu.my/71513/; https://www.dovepress.com/journal-of-asthma-and-allergy-journal

Objective: This systematic review aims to investigate the impact of collaborative practice between community pharmacist (CP) and general practitioner (GP) in asthma management. Methods: A systematic search was performed across 10 databases (PubMed, Medline/Ovid, CINAHL, Scopus, Web of Science, Cochrane central register of controlled trials, PsycARTICLES®, Science Direct, Education Resource Information Centre, PRO-Quest), and grey literature using selected MeSH and key words, such as '' community pharmacist'', ''general practitioner'' ''medicine use review''. The risk of bias of the included studies was assessed by Cochrane risk of bias tool. All studies reporting any of the clinical, humanistic, and economical outcomes using collaborative practice between CPs and GPs in management of asthma, such as CPs conducting medications reviews, patient referrals or providing education and counselling, were included. Results: A total of 23 studies (6 RCTs, 4 C-RCT, 3 controlled interventions, 7 pre-post and 3 case control) were included. In total, 11/14 outcomes were concluded in favor of CP-GP collaborative interventions with different magnitude of effect size. Outcomes, such as asthma severity, asthma control, asthma symptoms, PEFR, SABA usage, hospital visit, adherence and QoL (AQLQ, LWAQ) demonstrated a small effect size (d≥ 0.2) while, inhalation technique, ED visit and asthma knowledge witnessed medium ES (d≥ 0.5). In addition to that, inhalation technique yielded large ES (d≥ 0.8) in RCTs subgroup analysis. However, 3 outcomes, FEV, corticosteroids usage and preventer to reliever ratio did not hold significant ES (d< 0.2) and thus, remain inconclusive. The collaboration was shown to be value for money in the economic studies in narrative synthesis, however, limited number of studies hinder pooling of data in meta-analysis. Conclusion: The findings from this review established a comprehensive evidence base in support of the positive impact of collaborative practice between CP and GP in the management of asthma.