In silico structural and functional annotation of nine essential hypothetical proteins from Streptococcus pneumoniae

• Main Authors: Razali, Khairiah, Abdul Hamid, Azzmer Azzar, Md Zin, Noor Hasniza, Mohammad Bunnori, Noraslinda, Ahmad Yusof @Hanafi, Hanani, Kamarudin, Kamarul Rahim, Mohammed Rehan, Aisyah
• Format: Article
• Language: English
• Published: Chemistry Department, Universitas Gadjah Mada, Indonesia 2019
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/70283/1/Indonesial%20Journal%20Of%20Chemistry_In%20Press.pdf; http://irep.iium.edu.my/70283/; https://jurnal.ugm.ac.id/ijc/article/view/41817/24347

The ability of Streptococcus pneumoniae to induce infections relies on its virulence factor machinery. A previous CRISPR interference (CRISPRi) study had identified 254 essential proteins that may be responsible for the pathogenicity of S. pneumoniae serotype 2 strain D39. However, 39 of them were f...