Preliminary study of PAX9 single nucleotide polymorphism (rs8004560) in patients with Class II skeletal base malocclusion contributed by mandibular retrognatism

• Main Authors: Mohd Saad, Muhammadazril, Abd Rahman, Nur Amin, Mokhtar@Makhtar, Khairani Idah, Abu Bakar, Noraini, Kharuddin, Azrul Fazwan, Wan Taib, Wan Rohani
• Format: Article
• Language: English; English
• Published: Penerbit Universiti Sains Malaysia 2018
• Subjects: RK Dentistry
• Online Access: http://irep.iium.edu.my/68343/7/68343%20Preliminary%20study%20of%20PAX9%20single%20nucleotide.pdf; http://irep.iium.edu.my/68343/8/68343%20Preliminary%20study%20of%20PAX9%20single%20nucleotide%20WOS.pdf; http://irep.iium.edu.my/68343/; http://www.dental.usm.my/aos/docs/Vol_13/aos-article-0329.pdf

Polymorphism in PAX9 (rs8004560), a gene responsible for craniofacial and tooth development, is often associated with Class II/Div2 malocclusion. This study aimed to detect the presence of PAX9 SNP (rs8004560) and to determine its genotype and allele distribution in Class II skeletal base malocclu...