Naringin attenuates the development of carrageenan-induced acute lung inflammation through inhibition of NF-κb, STAT3 and pro-inflammatory mediators and enhancement of IκBα and anti-inflammatory cytokines

• Main Authors: Ahmad, Sheikh Fayaz, Attia, Sabry M., Bakheet, Saleh A., Zoheir, Khairy M. A., Ansari, Mushtaq Ahmad, Korashy, Hesham M., Abdel-Hamied, Hala E., Ashour, Abdelkader Elbadawy Abbas, Abd-Allah, Adel R. A.
• Format: Article
• Language: English; English
• Published: Springer Nature Switzerland AG. 2015
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/66957/1/Naringin%20Attenuates%20the%20Development%20of%20Carrageenan-Induced%20Acute%20Lung%20Inflammation%20Through%20Inhibition%20of%20NF-%CE%BAb%2C%20STAT3%20and%20Pro-Inflammatory%20Mediators%20and%20Enhancement%20of%20I%CE%BAB%CE%B1%20and%20Anti-Inflammatory%20Cytokines.pdf; http://irep.iium.edu.my/66957/7/66957_Scopus%20-%20Document%20details.pdf; http://irep.iium.edu.my/66957/; https://link.springer.com/journal/10753

Naringin has been reported to possess diverse pharmacological properties, including anti-arthritic and anti-inflammatory activities. The aim of the present study was to determine the potential anti-inflammatory effect of naringin in a mouse model of carrageenan-induced pleurisy. A single dose of nar...