Confocal laser scanning microscope analysis on post-biofilm assessment of biofilmproducing osteomyelitic staphylococcus aureus treated with new gentamicin-nigella sativa fusion emulsion (GNFE)

• Main Authors: Yaacob, Khairul Ikhwan, Mohd Shafri, Mohd Affendi, Mohd Yusof, Nazri, Mohamed, Farahidah
• Format: Article
• Language: English
• Published: Microscopy Society of Malaysia (MSM) 2015
• Subjects: QR Microbiology; R Medicine (General); RM147 Administration of Drugs and Other Therapeutic Agents
• Online Access: http://irep.iium.edu.my/66948/1/MJMicroscopy-2015-12%20%282%29.pdf; http://irep.iium.edu.my/66948/; http://mjm.msm.org.my/index.php/mjm/index

Biofilm complicates osteomyelitis as there is antibiotic resistance and toxicity involved. In order to overcome the challenges of current treatment, gentamicin, the current antibiotic of choice for osteomyelitis, is fused with Nigella sativa oil to form an emulsion. Its efficacy as anti-biofilm a...