Acinetobacter baumanniiphenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

• Main Authors: Bhuiyan, Md Saruar, Ellett, Felix, Murray, Gerald L., Kostoulias, Xenia, Cerqueira, Gustavo M., Schulze, Keith E., Mahamad Maifiah, Mohd Hafidz, Li, Jian, Creek, Darren J., Lieschke, Graham J., Peleg, Anton Y.
• Format: Article
• Language: English
• Published: National Academy of Sciences 2016
• Subjects: QR Microbiology
• Online Access: http://irep.iium.edu.my/65203/7/65203%20Acinetobacter%20baumannii%20phenylacetic%20acid%20metabolism.pdf; http://irep.iium.edu.my/65203/; http://www.pnas.org/content/pnas/113/34/9599.full.pdf

Innate cellular immune responses are a critical first-line defense against invading bacterial pathogens. Leukocyte migration from the bloodstream to a site of infection is mediated by chemotactic factors that are often host-derived. More recently, there has been a greater appreciation of the imp...