Prevention of brain hypoperfusion-induced neurodegeneration in rat's hippocampus by black cumin fixed oil treatment

• Main Authors: Azzubaidi, Marwan Saad, Al-Ani, Imad Matloub Dally, Saxena, Anil Kumar, Faisal, Ghasak Ghazi
• Format: Article
• Language: English; English; English
• Published: International Islamic University Malaysia 2018
• Subjects: QM Human anatomy; RB Pathology; RC Internal medicine; RM216 Diet Therapy. Clinical Nutrition
• Online Access: http://irep.iium.edu.my/65085/1/65085_Prevention%20of%20Brain%20Hypoperfusion-Induced%20_article.pdf; http://irep.iium.edu.my/65085/2/65085_Prevention%20of%20Brain%20Hypoperfusion-Induced%20_scopus.pdf; http://irep.iium.edu.my/65085/13/65085_Prevention%20of%20brain%20hypoperfusion-induced_WOS.pdf; http://irep.iium.edu.my/65085/; http://iiumedic.net/imjm/v1/download/volume_17_no_1/Vol17-No1-p103112.pdf

Introduction: The oil extract of black cumin seeds Nigella sativa (NSO) demonstrated considerable preservation of spatial cognitive functions in rats subjected to chronic brain hypoperfusion (CBH). The hippocampal CA1 region pyramidal cells are the earliest neurons suffering neurodegeneration follow...