Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kb ligand (RANKL) in subchondral bone during the development of osteoarthritis

• Main Authors: Akman, Akma Azmiera, Talib, Ain Aisyah, Md Yusof, Nur Azirah, Khalid, Kamarul Ariffin, Yusof, Nurul Asyiqin, Abdul Ghani, Radiah, Hamdan, Asmah Hanim, Zamli, Zaitunnatakhin
• Format: Conference or Workshop Item
• Language: English
• Published: 2018
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/64806/1/MSAB%202018%20abstract.pdf; http://irep.iium.edu.my/64806/

Osteoarthritis (OA) is a degenerative joint disease that is characterized by subchondral bone changes. Previous studies of OA have shown that structural changes were differed between subchondral bone plate (Sbp) and trabecular bone (Tb). However, the expression of OPG (bone formation) and RANKL (...