Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119

• Main Authors: Ahmad Arifin, Syamsul, Paternoster, Silvano, Carlessi, Rodrigo, Casari, Ilaria, Ekberge, Jeppe Hvidtfeldt, Maffucci, Tania, Newsholme, Philip, Rosenkilde, Mette M., Falasca, Marco
• Format: Article
• Language: English; English; English
• Published: Elsevier 2018
• Subjects: QH301 Biology; RM283 Endocrinotheraphy; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/64800/7/64800_Oleoyl-lysophosphatidylinositol%20enhances_SCOPUS.pdf; http://irep.iium.edu.my/64800/13/64800_Oleoyl-lysophosphatidylinositol%20enhances.pdf; http://irep.iium.edu.my/64800/19/64800_Oleoyl-lysophosphatidylinositol%20enhances%20_WoS.pdf; http://irep.iium.edu.my/64800/; https://www.sciencedirect.com/science/article/pii/S1388198118301288?via%3Dihub

The gastrointestinal tract is increasingly viewed as critical in controlling glucose metabolism, because of its role in secreting multiple glucoregulatory hormones, such as glucagon like peptide-1 (GLP-1). Here we investigate the molecular pathways behind the GLP-1- and insulin-secreting capabilitie...