Formation of fine and encapsulated mefenamic acid form I particles for dissolution improvement via electrospray method

• Main Authors: Zolkepali, Nurul Karimah, Abu Bakar, Noor Fitrah, Naim, M. Nazli, Anuar, Nornizar, Kamalul Aripin, Nurul Fadhilah, Abu Bakar, Mohd Rushdi, Lenggoro, I. Wuled, Kamiya, Hidehiro
• Format: Article
• Language: English; English; English; English
• Published: Taylor & Francis 2018
• Subjects: RS192 Materia Medica-Pharmaceutical Technology; TP155 Chemical engineering
• Online Access: http://irep.iium.edu.my/63406/1/2016_Rushdi_Formation%20of%20fine%20and%20encapsulated%20mefenamic%20acid.pdf; http://irep.iium.edu.my/63406/13/63406_Formation%20of%20fine%20and%20encapsulated%20mefenamic%20acid%20form%20I%20particles_article.pdf; http://irep.iium.edu.my/63406/7/63406_Formation%20of%20fine%20and%20encapsulated%20mefenamic%20acid_SCOPUS.pdf; http://irep.iium.edu.my/63406/19/63406%20Formation%20of%20fine%20and%20encapsulated%20mefenamic%20acid%20form%20I%20particles%20for%20dissolution%20improvement%20via%20electrospray%20method_wos.pdf; http://irep.iium.edu.my/63406/; https://www.tandfonline.com/doi/abs/10.1080/02726351.2016.1246496?journalCode=upst20

The potential of using electrostatic atomizer or electrospray in producing fine and encapsulated particle of mefenamic acid (MA) form I with β-cyclodextrin (βCD) was demonstrated in this study. Encapsulated MA-βCD with a molar ratio of 1:2 was prepared in water-ethanol suspension, followed by the e...