Porcupine bezoar exhibit cell cycle arrest through inhibiting cyclin /CDK1 complex and apoptosis mitochondria mediated dependent pathway in A549 cells

• Main Authors: Firus Khan, Al'aina Yuhainis, Abdullah Asuhaimi, Faizah, Abdull Rasad, Mohammad Syaiful Bahari, Mohamad, Mardhiah, Hashim, Ridzwan, Mamat, Suhana, Johan, Muhammad Farid, Abdul Wahab, Ridhwan
• Format: Conference or Workshop Item
• Language: English
• Published: 2016
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/60467/1/pan%20asian.pdf; http://irep.iium.edu.my/60467/

Porcupine bezoar (PB) previously reported to possess various medical properties, however there is no information on its potential anticancer effect on human cancer cells. In this study we investigate potential apoptotic effects induced by PB extracts in A549 cells and elucidate the underlying mec...