Epigenetic changes of DRD2 gene in pathogenesis of schizophrenia

• Main Authors: Abd. Rahim, Nour El Huda, Rahim, Mohd Nabil Fikri, Ku Zaifah, Norsidah, Mohd Noor, Hanisah, Abdullah, Kartini, A. Talib, Norlelawati
• Format: Conference or Workshop Item
• Language: English
• Published: Kulliyyah of Medicine, International Islamic University Malaysia 2017
• Subjects: RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
• Online Access: http://irep.iium.edu.my/59600/1/59600_EPIGENETIC%20CHANGES.pdf; http://irep.iium.edu.my/59600/; http://iiumedic.net/imjm/v1/about-imjm/

Introduction: The dopamine hypothesis has earlier dominated the theories for the development of schizophrenia based on the early pharmacologic evidence. The antipsychotic drugs, among others, is thought to interfere with the function of the dopamine D2 receptor (DRD2) resulting in clinical improveme...