A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal aortic aneurysm

• Main Authors: Abdul Rahman, Mohd Norhisham Azmi, Khan, Junaidalam, Mazari, Fayyaz Ali Khan, Mockford, Katherine, McCollum, Peter Thomas, Chetter, Ian Clifford
• Format: Article
• Language: English
• Published: Elsevier 2011
• Subjects: RD Surgery
• Online Access: http://irep.iium.edu.my/59244/1/A%20randomised%20placebo%20controlled%20trial%20of%20the%20effect%20of%20preoperative%20statin.pdf; http://irep.iium.edu.my/59244/; http://www.annalsofvascularsurgery.com/article/S0890-5096(10)00300-6/fulltext

BACKGROUND: A double-blind, randomized controlled trial was carried out to study the effects of statins on matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in areas of peak and low abdominal aortic aneurysm (AAA) wall stress. METHODS: A total of 40 patie...