Lactogenic effects of tannin and aglycone form of aqueous extract (AFAE) from Musa x paradisiaca flower on lactating rats.

• Main Authors: Mahmood, Azizah, Noor, Salihah, Omar, Muhammad Nor, Ngah, Nurziana
• Format: Article
• Language: English; English
• Published: Malaysian Society of Applied Biology 2017
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/58875/1/Lactogenic%20Banana%20Dr%20Azizah%20Mahmood%2046_03_02.pdf; http://irep.iium.edu.my/58875/2/Lactogenic%20Dr%20Azizah%20Scopus%20-%20Document%20details.pdf; http://irep.iium.edu.my/58875/; http://pkukmweb.ukm.my/msab/

This research is aimed to investigate the in vivo lactogenic effects of Musa x paradisiaca flower extracts, namely the aglycone form of aqueous extract (AFEA) and condensed tannin (CT) on lactating rats. Lactating rats (n=6) of Spraque Dawley with six pups each were orally administered with aqueous extract, AFEA, CT and metoclopramide. They were daily administered starting Day 5 until Day 14 and the performance was measured by weight-suckle-weight method. Results were analysed using SPSS by means of ANOVA at 0.05 and was expressed as their mean ± standard deviation. Milk production of rats treated with AFAE (4.65 ± 1.67 gm/pup/day) and aqueous extract (4.86 ± 2.36 gm/pup/day) were comparable with each other and significantly higher than negative control (3.63 ± 2.10 gm/pup/day) group. The groups treated with aqueous, AFAE, metoclopramide and CT were observed to increase milk yield by 28.03%, 24.87%, 2.63% and 2.20%, respectively, compared to negative control. The percentage body weight increment of pups for aqueous extract, AFAE, negative control, metoclopramide and CT, respectively were 148.21%, 122.29%, 113.8%, 101.53% and 87.06%. This research reveals the potential efficacy of bioactive compounds from Musa x paradisiaca flower to enhance milk production of inadequate supply of milk for breastfeeding mothers.