An autonomous lab on a chip for space flight calibration of gravity-induced transcellular calcium polarization in single-cell fern spores

• Main Authors: Park, J.H., Salmi, Mari L., Wan Salim, Wan Wardatul Amani, Rademacher, A.T., Wickizer, B., Schooley, Aaron, Benton, J.E., Cantero, A., Argote, P., Ren, M., Zhang, Min, Porterfield, David Marshall, Ricco, Antonio J., Roux, S. J., Rickus, Jenna L.
• Format: Article
• Language: English; English; English
• Published: Royal Society of Chemistry 2017
• Subjects: T Technology (General)
• Online Access: http://irep.iium.edu.my/56923/1/2017_SporeSat%20Ground-LoaC.pdf; http://irep.iium.edu.my/56923/9/56923_An%20autonomous%20lab%20on%20a%20chip_SCOPUS.pdf; http://irep.iium.edu.my/56923/15/56923_An%20autonomous%20lab%20on%20a%20chip%20for%20space_article.pdf; http://irep.iium.edu.my/56923/; https://www.ncbi.nlm.nih.gov/pubmed/28205656

This report describes the development of lab-on-a-chip device designed to measure changes in cellular ion gradients that are induced by changes in gravitational (g) forces. The bioCD presented here detects differential calcium ion concentrations outside of individual cells. The device includes suffi...