Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line

• Main Authors: Mohd Hussain, Nurlaili Najmie, Uzir, Bisha Fathamah, Mohd Hassan, Norazian
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2016
• Subjects: RM Therapeutics. Pharmacology; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/54885/29/54885.pdf; http://irep.iium.edu.my/54885/30/54885-certificate-1.pdf; http://irep.iium.edu.my/54885/

Arborinine is an acridone alkaloid found exclusively in Rutacae family has been shown to inhibit proliferation of a wide variety of cancer cell lines. The present study is aimed to isolate and investigate the anti-proliferative activity of arborinine, isolated from a Malaysian Rutaceae, G. pentapyll...