In vitro and in vivo gene expression studies of cartilage-like tissue engineered construct using a combination of transiently transfected human osteoarthritic chondrocytes and tissue engineering technique

• Main Authors: Sha'ban, Munirah, Mohamad Sukri, Norhamiza, Zulkifly, Ahmad Hafiz
• Format: Conference or Workshop Item
• Language: English; English
• Published: Frontiers Media 2016
• Subjects: TA164 Bioengineering
• Online Access: http://irep.iium.edu.my/54740/1/Munirah%206thMTERMS2016%20Abstract.pdf; http://irep.iium.edu.my/54740/7/54740_In%20vitro%20and%20in%20vivo%20gene%20expression.pdf; http://irep.iium.edu.my/54740/

Purpose: To evaluate the formation of cartilage-like tissue engineered constructs (TECs) using human osteoarthritic chondrocytes overexpressed with SOX9 gene seeded on poly(lactic-co-glycolic acid) (PLGA) with and without fibrin scaffolds through cartilaginous genes expression analysis. Methods:...