Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models

• Main Authors: Zakaria, Zainul Amiruddin, Jaios, Ermansyah, Omar, MH, Abdul Rahman, Suzanah, Hamid, SSA, Ching, Siewmooi, Teh, Lay Kek, Salleh, Mohd Zaki, Darnis, Deny Susanti, Bakhtiar, M. Taher
• Format: Article
• Language: English; English; English
• Published: BioMed Central Ltd 2016
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/53235/1/53235_Antinociception%20of%20petroleum.pdf; http://irep.iium.edu.my/53235/2/53235_Antinociception%20of%20petroleum_WOS.pdf; http://irep.iium.edu.my/53235/3/53235_Antinociception%20of%20petroleum_SCOPUS.pdf; http://irep.iium.edu.my/53235/; http://bmccomplementalternmed.biomedcentral.com/

Background: Melastoma malabathricum L. (family Melastomaceae) has been traditionally used as remedies against various ailments including those related to pain. The methanol extract of M. malabathricum leaves has been proven to show antinociceptive activity. Thus, the present study aimed to determine...