The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
The aim of this study was to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde from Cinnamomum burmannii on the cell membrane of Escherichia coli, Staphylococcus aureus and Candida albicans. The essential oil was extracted by steam distillation and followed by t...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Universiti Teknologi Malaysia
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/53158/7/53158_The%20mode%20of%20antimicrobial%20action%20of%20Cinnamomum_Scopus.pdf http://irep.iium.edu.my/53158/13/53158_The%20mode%20of%20antimicrobial%20action.pdf http://irep.iium.edu.my/53158/14/53158_The%20mode%20of%20antimicrobial%20action_WOS.pdf http://irep.iium.edu.my/53158/ http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/9942/5980 |
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| Summary: | The aim of this study was to postulate the mode of antimicrobial actions of both
essential oil and cinnamaldehyde from Cinnamomum burmannii on the cell
membrane of Escherichia coli, Staphylococcus aureus and Candida albicans. The
essential oil was extracted by steam distillation and followed by the isolation of
cinnamaldehyde. Four modes of action were tested including time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. The
antimicrobial effect on the cell membrane was dose-dependent whereby stronger
antimicrobial action was observed by cinnamaldehyde at concentration equal to
4×MIC (1.33 mg/mL) compared to the essential oil. The potential of cinnamaldehyde
as an antimicrobial compound of the cinnamon essential oil was discovered and
proven to act on the cell membrane of tested microorganisms particularly against C. albicans. |
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