Development and validation of high performance liquid chromatography method for analysis of Raloxifene HCl in rat plasma by liquid –liquid extraction

• Main Authors: Mahmood, Syed, Bakhtiar, M. Taher, Mandal, Uttam Kumar
• Format: Conference or Workshop Item
• Language: English
• Published: Kulliyyah of Pharmacy, International Islamic University Malaysia 2016
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/51874/13/51874-new.pdf; http://irep.iium.edu.my/51874/; http://www.iium.edu.my/icip2016/

A new, simple and sensitive HPLC method was developed for the quantification of raloxifene in rat plasma. Samples were prepared by liquid- liquid extraction method together with diclofenac sodium as internal standard (IS) at 2 μg/ml concentration. Separation of raloxifene from the treated samples wa...