Blood-pressure and cholesterol lowering in persons without cardiovascular disease

• Main Authors: Yusuf, Salim, Phi, D., Lonn, Eva, Pais, Prem, Bosch, Jackie, López‑Jaramillo, Patricio, Md Aris, Mohd Aznan, Mohd Shah, Azarisman Shah, ., et. al
• Format: Article
• Language: English; English; English
• Published: Massachusetts Medical Society 2016
• Subjects: R Medicine (General); RJ Pediatrics; RZ Other systems of medicine
• Online Access: http://irep.iium.edu.my/50347/9/Dr_Aznan_Blood-Pressure_and_Cholesterol_Lowering.pdf; http://irep.iium.edu.my/50347/12/nejmoa1600177_appendix.pdf; http://irep.iium.edu.my/50347/13/50347_Blood-Pressure_and_Cholesterol_Lowering_wos_scopus.pdf; http://irep.iium.edu.my/50347/; http://www.nejm.org/doi/full/10.1056/NEJMoa1600177#t=article

Elevated blood pressure and elevated low-density lipoprotein (LDL) cholesterol increase the risk of cardiovascular disease. Lowering both should reduce the risk of cardiovascular events substantially. In a trial with 2-by-2 factorial design, we randomly assigned 12,705 participants at intermed...