Review on in-vitro amebocyte culture–a lesson learned from past

• Main Authors: Sheikh, Hassan Ibrahim, John, Akbar, Ichwan, Solachuddin J. A., Kassim, Zaleha, Yunus, Kamaruzzaman
• Format: Article
• Language: English
• Published: Universiti Teknologi Malaysia 2015
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/46678/1/6759-18553-1-SM.pdf; http://irep.iium.edu.my/46678/; http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/6759; http://dx.doi.org/10.11113/jt.v77.6759

Limulus Amebocyte Lysate (LAL/TAL) assay is the only standard test approved by the Food and Drug Administration (FDA) to quantify bacterial endotoxin in injectable drugs and implantable medical devices. At present, horseshoe crabs are the sole source of LAL/TAL. Biomedical companies harvest and blee...