A novel animal model for subcutaneous soft tissue infection using temporally neutropenic lys-EGFP mice

• Main Authors: Zulaziz, N., Azhim, Azran, Miyazaki, H., Kinoshita, M., Himeno, N., Saitoh, D., Morimoto, Y.
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2015
• Subjects: TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/44920/1/A_Novel_Animal_Model_for_Subcutaneous_Soft.pdf; http://irep.iium.edu.my/44920/4/ascc_proceeeding_cove%2C_copyright%2C_content.pdf; http://irep.iium.edu.my/44920/; http://dx.doi.org/10.1109/ASCC.2015.7244500

Neutrophils play an important role against bacterial infection, mainly methicillin resistant Staphylococcus aureus (MRSA). Therefore, we developed an animal model to simultaneously monitor bacterial colonization and neutrophil migration in vivo. Using lys-EGFP C57BL/6 mice, we initially rendered the...