Cartilaginous markers expression in human articular chondrocytes overexpressed with SOX9 gene

• Main Authors: Mohamad Sukri, Norhamiza, Mat Jusoh, Nurul Syamimi, Mohadis, Hanisah Mohd, Md Nazir, Noorhidayah, Abdul Rahman, Rozlin, Ahmad Radzi, Muhammad Aa'zamuddin, Zulkifly, Ahmad Hafiz, Hashi, Abdurezak Abdulahi, Mohammad, Mohd Yusof, Sha'ban, Munirah
• Format: Article
• Language: English
• Published: Tissue Engineering and Regenerative Medicine Society of Malaysia 2014
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/41426/1/RR-181114-074.pdf; http://irep.iium.edu.my/41426/; http://www.regres.tesma.org.my/pdf/RR-181114-074.pdf

SOX9 is an essential transcription factor for chondrocyte differentiation and cartilage formation. The limited regenerative capacity of cartilage has led to the development of various treatment modality including gene transfer approaches. In this study, we transiently overexpressed or transfected SO...