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Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum

Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to pre...

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Main Authors: Noorbatcha, Ibrahim Ali, Ahmad, Abdul Aziz, Mohd. Salleh, Hamzah
Format: Conference or Workshop Item
Language:English
English
Published: 2014
Subjects:
TP Chemical technology
TP248.13 Biotechnology
Online Access:http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf
http://irep.iium.edu.my/41304/4/computational_prediction.pdf
http://irep.iium.edu.my/41304/
http://www.iium.edu.my/irie/14/
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spelling my.iium.irep.413042021-06-30T08:09:55Z http://irep.iium.edu.my/41304/ Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum Noorbatcha, Ibrahim Ali Ahmad, Abdul Aziz Mohd. Salleh, Hamzah TP Chemical technology TP248.13 Biotechnology Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to predict thermostable endoglucanase. The molecular dynamics simulation is a powerful tool that can be used to study the enzymes behaviour at high temperature. On the basis of computer simulations we have predicted a mutant endoglucanase with improved thermal stability properties. 2014-06-11 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf application/pdf en http://irep.iium.edu.my/41304/4/computational_prediction.pdf Noorbatcha, Ibrahim Ali and Ahmad, Abdul Aziz and Mohd. Salleh, Hamzah (2014) Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum. In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014), 11th -13th June 2014, Cultural Activity Center (CAC), Internatioanal Islamic University Malaysia. (Unpublished) http://www.iium.edu.my/irie/14/
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic TP Chemical technology
TP248.13 Biotechnology
spellingShingle TP Chemical technology
TP248.13 Biotechnology
Noorbatcha, Ibrahim Ali
Ahmad, Abdul Aziz
Mohd. Salleh, Hamzah
Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
description Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to predict thermostable endoglucanase. The molecular dynamics simulation is a powerful tool that can be used to study the enzymes behaviour at high temperature. On the basis of computer simulations we have predicted a mutant endoglucanase with improved thermal stability properties.
format Conference or Workshop Item
author Noorbatcha, Ibrahim Ali
Ahmad, Abdul Aziz
Mohd. Salleh, Hamzah
author_facet Noorbatcha, Ibrahim Ali
Ahmad, Abdul Aziz
Mohd. Salleh, Hamzah
author_sort Noorbatcha, Ibrahim Ali
title Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_short Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_full Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_fullStr Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_full_unstemmed Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_sort computational prediction and development of a thermostable endoglucanase i from fusarium oxysporum
publishDate 2014
url http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf
http://irep.iium.edu.my/41304/4/computational_prediction.pdf
http://irep.iium.edu.my/41304/
http://www.iium.edu.my/irie/14/
_version_ 1705056473717932032
score 13.18916

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