Understanding the immune responses in granuloma formation through agent-based simulation

• Main Authors: Al Haek, Mohammed, Ismail , Amelia Ritahani
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2014
• Subjects: QA75 Electronic computers. Computer science
• Online Access: http://irep.iium.edu.my/40820/1/Understanding__the_Immune_Responses_in_Granuloma_Formation_through_Agent-based_Simulation.pdf; http://irep.iium.edu.my/40820/8/Amelia_immune_response.pdf; http://irep.iium.edu.my/40820/

Granuloma formation is a medical condition that occurs as a result of infection of bacteria to the host, which include getting rid of unwanted substances, destroying pathogen, enhancing immunity by stimulating the macrophages following the T-lymphocytes contained in it. Granuloma appears in diseases such as Mycobacterium Tuberculosis and Visceral Leishmaniasis. Although granuloma is a host-defense mechanism for containing bacteria, it also contribute to early bacterial growth and shelters the bacteria thus they can spread later and it might be harmful.