Biodegradable poly(D,L-lactic-co-glycolic acid)-based micro/nanoparticles for sustained release of protein drugs - a review

• Main Authors: Ansary , Rezaul H., Awang, Mohamed Bin, Rahman, Md. Mokhlesur
• Format: Article
• Language: English
• Published: Pharmacotherapy Group, Faculty of Pharmacy, University of Benin 2014
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/37845/1/Tropical_Journal_2014_%282014_13_7_24.pdf%29.pdf; http://irep.iium.edu.my/37845/; http://www.tjpr.org/vol13_no7/2014_13_7_24_download.html

Biodegradable poly(D, L-lactide-co-glycolide) (PLGA) and PLGA-based polymeric nanoparticles are widely used for sustained release of protein and peptide drugs. These formulations are usually prepared by water/oil/water (W/O/W) and solid/oil/water (S/O/W) double emulsion solvent evaporation method....