Isolation and characterization of a presynaptic neurotoxin, P-elapitoxin-Bf1a from Malaysian bungarus fasciatus venom

• Main Authors: Ahmad Rusmili, Muhamad Rusdi, Ting, Tee Yee, Mustafa, Mohd Rais, Hodgson, Wayne C., Othman, Iekhsan
• Format: Article
• Language: English; English; English
• Published: Elsevier Inc. 2014
• Subjects: QH301 Biology; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/37576/1/2014_Rusmili_BiochemPharma_Presynaptic.pdf; http://irep.iium.edu.my/37576/4/37576_Isolation%20and%20characterization%20of%20a%20presynaptic%20neurotoxin_SCOPUS.pdf; http://irep.iium.edu.my/37576/5/37576_Isolation%20and%20characterization%20of%20a%20presynaptic%20neurotoxin_WoS.pdf; http://irep.iium.edu.my/37576/; http://www.sciencedirect.com/science/article/pii/S0006295214003888; http://dx.doi.org/10.1016/j.bcp.2014.07.001

Presynaptic neurotoxins are one of the major components in Bungarus venom. Unlike other Bungarus species that have been studied, β-bungarotoxin has never been isolated from Bungarus fasciatus venom. It was hypothesized that the absence of β-bungarotoxin in this species was due to divergence during e...