Chronic khat consumption and its effect on ovarian structure in mice and their offspring
Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight...
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Department of Anatomy, National University of Singapore
2014
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my.iium.irep.36823 http://irep.iium.edu.my/36823/ Chronic khat consumption and its effect on ovarian structure in mice and their offspring AlBadri, Cinaria Al-Ani, Imad Matloub Dally Hiba, Hassan QL Zoology Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight of khat extract by gastric gavage for 4 and 8 weeks. After four weeks of treatment, the male and female mice were allowed to mate. Khat treatment continued for the male mice and for the female mice during pregnancy and after giving birth to their offsprings up to 8 weeks. Adult offspring and their parent were killed at the 4th and 8th weeks of treatment. Histological examination of the ovaries showed many corpus luteum and developing Graafi an follicles with mononuclear infi ltration. Department of Anatomy, National University of Singapore 2014-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36823/1/Chronic_Khat_Consumption.pdf AlBadri, Cinaria and Al-Ani, Imad Matloub Dally and Hiba, Hassan (2014) Chronic khat consumption and its effect on ovarian structure in mice and their offspring. Annals of Microscopy, 14. pp. 64-69. ISSN 0219-2209 http://www.microscopy.org.sg/journal/vol_14/Annals%20of%20Microscopy%20Vol%2014-Web.pdf |
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QL Zoology AlBadri, Cinaria Al-Ani, Imad Matloub Dally Hiba, Hassan Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
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Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this
study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve
male and twelve female mice were given orally a dose of 50mg/kg body weight of khat extract by gastric
gavage for 4 and 8 weeks. After four weeks of treatment, the male and female mice were allowed to mate.
Khat treatment continued for the male mice and for the female mice during pregnancy and after giving birth to
their offsprings up to 8 weeks. Adult offspring and their parent were killed at the 4th and 8th weeks of treatment.
Histological examination of the ovaries showed many corpus luteum and developing Graafi an follicles with
mononuclear infi ltration. |
format |
Article |
author |
AlBadri, Cinaria Al-Ani, Imad Matloub Dally Hiba, Hassan |
author_facet |
AlBadri, Cinaria Al-Ani, Imad Matloub Dally Hiba, Hassan |
author_sort |
AlBadri, Cinaria |
title |
Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
title_short |
Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
title_full |
Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
title_fullStr |
Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
title_full_unstemmed |
Chronic khat consumption and its effect on ovarian structure in mice and their offspring |
title_sort |
chronic khat consumption and its effect on ovarian structure in mice and their offspring |
publisher |
Department of Anatomy, National University of Singapore |
publishDate |
2014 |
url |
http://irep.iium.edu.my/36823/1/Chronic_Khat_Consumption.pdf http://irep.iium.edu.my/36823/ http://www.microscopy.org.sg/journal/vol_14/Annals%20of%20Microscopy%20Vol%2014-Web.pdf |
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