Effects of different types of growth media on metabolite profiles (GCMS-based) of CHO-K1 cells expressing IGF-1 proteins

• Main Authors: Mohamed Saberi, Salfarina Ezrina, Hashim, Yumi Zuhanis Has-Yun, Packeer Mohamed, Vasila, Amid, Azura, Ahmad Raus, Raha, Mel, Maizirwan, Gibney, Michael J., Brennan, Lorraine, Al-Rubeai, Mohamed
• Format: Conference or Workshop Item
• Language: English
• Published: 2011
• Subjects: TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/3645/1/Paper_CHO_Salfarina.pdf; http://irep.iium.edu.my/3645/; http://www.iium.edu.my/icbioe/2011/

The use of mammalian cell lines especially Chinese Hamster Ovary-K1 (CHO-K1) cells for expression of recombinant proteins with potential therapeutic use such as viral vaccines, monoclonal antibodies, recombinant glycoproteins and blood clotting factors has become increasingly prevalent. An efficient...