Development and improvement of anti-gout property from aqueous-methanol extract of morinda elliptica using central composite design

• Main Authors: Jamal, Parveen, Azmi, Saiful Mohammad Nizam, Amid, Azura, Mohd. Salleh, Hamzah, Hashim, Yumi Zuhanis Has-Yun
• Format: Article
• Language: English; English
• Published: AENSI Publications 2014
• Subjects: T Technology (General); TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/36413/1/734-743_Parveen_.pdf; http://irep.iium.edu.my/36413/4/36413_Development%20and%20improvement%20of%20anti-gout_SCOPUS.pdf; http://irep.iium.edu.my/36413/; http://www.aensiweb.com/old/aeb/2014/734-743.pdf

Xanthine oxidase (XO) is a key enzyme in hyperuricemia, catalyzing the oxidation of hypoxanthine to xanthine and then to uric acid. Excess serum accumulated with uric acid leads to a type of arthritis known as gout. In this study, development of process conditions for XO inhibitory activity from...