Survival of lung cancer patients in a resource-limited country
Aim: Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. Method: All patients diagnosed with lung cancer from August 2007 to August 2010 were...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
John Wiley & Sons
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/34285/3/lung_cancer_acceptance_e_mail.jpeg http://irep.iium.edu.my/34285/7/Lung_cancer_AJCO.pdf http://irep.iium.edu.my/34285/10/Surviva_of_lung_cancer_patients.pdf http://irep.iium.edu.my/34285/ http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291743-7563 |
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| Summary: | Aim:
Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the
survival of our lung cancer patients and to determine independent prognostic factors affecting survival.
Method:
All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from
a single referral hospital of the state of Pahang, Malaysia. Detailed demographic data, ECOG (Eastern
Cooperation Oncology Group) performance status, stage of disease and treatment were recorded. The date
of histology or cytology confirmation was used as the date of entry. Survival time was calculated from the
date of entry to the date of death.
Results:
One hundred forty-nine patients were included for survival analysis. The median age was 62 years
and patients were predominantly males (78%) and smokers (78%). The majority had non-small cell lung
cancer (NSCLC) (94%); only six patients (4%) had small cell lung cancer. All patients presented with stage
3 or stage 4 disease. Overall median survival was 18 weeks. “No definitive treatment” and “ECOG 3–4”
were the significant independent predictors of death, with the hazard ratios of 2.1 (95% confidence interval
[CI] 1.4, 3.0) and 1.6 (95% CI 1.1, 2.3) times, respectively. Among NSCLC patients on treatment, 1- and
2-year survival rates were 27% and 15%, respectively.
Conclusion:
The majority of lung cancer patients in Pahang presented with advanced disease. No definitive
treatment and ECOG 3–4 were independent poor prognostic factors. |
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