Extensive Inflammatory Pseudotumour of cranial base – a rare case which has responded well to cyclophosphamide and steroid therapy

• Main Authors: Abdullah, Kahairi, Raja Lope Ahmad, Raja Ahmad Al'konee, Leman, Wan Ishlah, K.S, Sathananthar
• Format: Conference or Workshop Item
• Language: English
• Published: 2010
• Subjects: RF Otorhinolaryngology
• Online Access: http://irep.iium.edu.my/33397/1/Abstract_for_MSO-HNS_AGM.docx; http://irep.iium.edu.my/33397/; http://www.msohns.com/article.php?aid=112

Introduction: Inflammatory Pseudotumour (IP) of the head and neck is a rare disease. Due its rarity, diagnosis is often delayed which cause significant morbidity to the patient. Objective: To illustrate a case of extensive inflammatory pseudotumour involving the floor of cranial base which demonstrate an aggressive behavior clinically and radiologically. Treatment and Result: The clinical presentations were improved with oral cyclophosphamide in combination with oral steroid which were given for a period of three month. Conclusion: This case has illustrated a rare extensive IP of cranial base which responded well toward combination of cyclophosphamide and high dose steroid.